Partner proteins |
ATN1, ACVR2A, ADRB1, ATN1, CTNNB1, CTNND2, DLL1, DSCAML1, GRID2, MAGI2, PLXNB3, PTEN, RAPGEF2, SMAD3, TGFA, ACVR2A, ATN1 |
Description of target |
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. |