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MRGPRX2 Peptide - middle region (AAP59914)

MRGPRX2 Peptide - middle region (AAP59914)

Item no.	AAP59914
Manufacturer	AVIVA Systems Biology
Amount	100ug
Category	Peptides & Proteins Western Blot Peptides
Type	Peptides
Format	Lyophilized powder
Applications	WB
Specific against	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	MRGX2
Similar products	MRGPRX2
Available
Description	This is a synthetic peptide designed for use in combination with anti-MRGPRX2 Antibody (ARP59914_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	MRGPRX2
Protein size	330
Molecular weight	37kDa
Product format	Lyophilized powder
Gene id	117194
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins	CORT
Description of target	MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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