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Eya4 Peptide - middle region (AAP39975)

Eya4 Peptide - middle region (AAP39975)

Manufacturer	AVIVA Systems Biology
Category	Peptides & Proteins Western Blot Peptides
Type	Peptides
Specific against	Human, Mouse
Format	Lyophilized powder
Applications	WB
Amount	100ug
Item no.	AAP39975
eClass 6.1	34160400
eClass 9.0	32160409
Available
Alias	B130023L16Rik
Description	This is a synthetic peptide designed for use in combination with anti-Eya4 Antibody (ARP39975_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	Eya4
Protein size	616
Molecular weight	67kDa
Product format	Lyophilized powder
Gene id	14051
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins	Eya4, Six1, Six2
Description of target	Eya4 is a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Eya4 promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. It may be involved in development of the eye.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 8/9/2024

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