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PKLR (Human) cDNA (1ug)

PKLR (Human) cDNA (1ug)

Item no.	ANA11291
Manufacturer	AVIVA Systems Biology
Amount	1ug
Category	Nucleic Acids DNA cDNA
Type	cDNA
Specific against	other
ECLASS 10.1	32160414
ECLASS 11.0	32160414
UNSPSC	41105324
Similar products	PKLR
Available
description	The ORF of human PKLR is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-PKLR polyclonal antibody.
gene_symbol	PKLR
nucleotide_accession_num	http://www.ncbi.nlm.nih.gov/nuccore/BC025737
gene_id	5313
reconstitution_and_storage	Centrifuge the vials after receiving and add 5 ?l ddH2O
description_of_target	The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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