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CDK12 ELISA Kit (Mouse) (OKEH05056)

CDK12 ELISA Kit (Mouse) (OKEH05056)

Manufacturer	AVIVA Systems Biology
Category	ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Specific against	other
Amount	96 Wells
Item no.	OKEH05056
eClass 6.1	32160605
eClass 9.0	32160605
Available
Gene symbol	CDK12
Protein name	Cyclin-dependent kinase 12
Protein size	1484
Gene id	69131
Reconstitution and storage	Store as indicated in product manual.
Description of target	Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Assay info	Assay Methodology: Quantitative Sandwich ELISA
Sensitivity	41 pg/mL
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 96 Wells

available

Delivery expected until 7/26/2024