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PIN1 ELISA Kit (Mouse) (OKEH05048)

PIN1 ELISA Kit (Mouse) (OKEH05048)

Item no.	OKEH05048
Manufacturer	AVIVA Systems Biology
Amount	96 Wells
Category	ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Specific against	other
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Available
Gene symbol	PIN1
Protein name	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Protein size	165
Gene id	23988
Reconstitution and storage	Store as indicated in product manual.
Description of target	Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs in a subset of proteins, resulting in conformational changes in the proteins. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
Assay info	Assay Methodology: Quantitative Sandwich ELISA
Sensitivity	41.5 pg/mL
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 96 Wells

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Delivery expected until 9/27/2024