TJP1 ELISA Kit (Human) (OKCD00320)

tight junction protein ZO-1

7082

The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.1 Publication < p>Manually curated information for which there is published experimental evidence.< /p> < p>< a href="/manual/evidences#ECO:0000269">Moreâa‚¬A< /a>< /p> Manual assertion based on experiment iniRef.27"Cdc42-dependent formation of the ZO-1/MRCKbeta complex at the leading edge controls cell migration."_x005F_x000D_ Huo L., Wen W., Wang R., Kam C., Xia J., Feng W., Zhang M._x005F_x000D_ EMBO J. 30:665-678(2011) [PubMed] [Europe PMC] [Abstract]Cited for: STRUCTURE BY NMR OF 1631-1748 OF MUTANT 1699-MET-CYS-1700 IN COMPLEX WITH MYZAP, FUNCTION, SUBCELLULAR LOCATION, MUTAGENESIS OF 1699-MET-CYS-1700 AND PHE-1748, INTERACTION WITH MYZAP AND CDC42BPB.

< 0.059 ng/mL