Comparison

SNCA Antibody (Phospho-Tyr133) (OASG06962)

Item no. OASG06962
Manufacturer AVIVA Systems Biology
Amount 100 uL
Category
Type Antibody Polyclonal
Applications WB, IHC
Specific against other
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Gene symbol
SNCA
Molecular weight
50/15 kDa
Product format
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene id
6622; 20617; 29219
Reconstitution and storage
Store at -20C. Avoid repeated freeze/thaw cycles.
Description of target
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer' s disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human Synuclein- Alpha around the phosphorylation site of Y133. Location: 60-140aa.
Drywet
Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 uL
Available: In stock
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