Comparison

IGF1R Antibody (OASG03736)

Item no. OASG03736
Manufacturer AVIVA Systems Biology
Amount 100 uL
Category
Type Antibody Polyclonal
Applications WB, IHC
Specific against other
Host Rabbit
Isotype IgG
ECLASS 5.1 32160702
ECLASS 6.1 32160702
ECLASS 8.0 32160702
ECLASS 9.0 32160702
ECLASS 10.0.1 32160702
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Molecular weight
150 kDa
Product format
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene id
3480; 3643; 16001; 16337; 25718
Reconstitution and storage
Store at -20C. Avoid repeated freeze/thaw cycles.
Description of target
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human IGF-IR around the non-phosphorylation site of Y1161. Location: 1100-1180aa.
Drywet
Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 uL
Available: In stock
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