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MAP3K1 Antibody (OALA02678)

MAP3K1 Antibody (OALA02678)

Item no.	OALA02678
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG kappa
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MAP3K1, MAPK/ERK kinase kinase 1, MAPKKK1, MAP/ERK kinase kinase 1, MEK kinase 1, MEKK, MEKK 1, MEKK1, SRXY6
Similar products	MAP3K1, MEKK1, MAPK/ERK kinase kinase 1, MAPKKK1, MEKK, MAP/ERK kinase kinase 1, MEK kinase 1, SRXY6, MEKK 1
Available
Description	MEKK1, a MAP3K type protein kinase, is a member of the stress-activated protein kinase (SAPK) pathways which convey pro-apoptotic signals. The protein consists of a C-terminal protein kinase domain and an extensive N-terminal domain that includes two proline-rich segments containing putative binding sites for proteins with SH3 domains, a consensus binding site for 14-3-3 proteins, two PH domains and an acid rich motif with two sites for cleavage by proapoptotic caspase cysteine proteases.
Gene symbol	MAP3K1
Alias symbols	MAP3K1, MAPK/ERK kinase kinase 1, MAPKKK1, MAP/ERK kinase kinase 1, MEK kinase 1, MEKK, MEKK 1, MEKK1, SRXY6
Gene_id	4214
Reconstitution and storage	+4C or -20C, Avoid repeated freezing and thawing.
Specificity	Reacts specifically with MEKK1 protein detecting a monomer species migrating at ca.69kD and a trimer species migrating at ca.200kD. Cross-reactivity with other proteins has not been observed. Species cross-reactivity:MEKK1. Tested by Western blotting with HeLa, 293 (kidney) and MEKK1 transfected cells.
Purification	Affinity purified
Warning	For research use only.
Immunogen	MAP3K1 / MEKK1 antibody was raised against recombinant protein encompassed within amino acids 130-300 of the human MEKK1 protein.
Application Info	IHC - Paraffin (5 ug/ml), Western blot (1 - 3 ug/ml), ELISA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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