« Back
Home /
CLDN18 Antibody (OAAF08291)

CLDN18 Antibody (OAAF08291)

Item no.	OAAF08291
Manufacturer	AVIVA Systems Biology
Amount	50ul
Category	Antibodies Immunohistochemistry Primary Antibodies
Type	Antibody Monoclonal
Applications	IHC-P
Specific against	Human
Host	Mouse
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Gene symbol	CLDN18
Protein name	claudin-18
Molecular weight	28A kDa
Product format	Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20
Gene id	51208
Reconstitution and storage	Shipped at 4C. Store at -20C. Stable for 12 months at -20C.
Description of target	This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification	Immunogen affinity purified
Clonality	Monoclonal
Immunogen	The antiserum was produced against synthesized peptide derived between 220-261 aa of human CLDN18. The exact sequence is proprietary.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50ul

available

Delivery expected until 9/27/2024