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MCP-1 Antibody (OAAD00411)

MCP-1 Antibody (OAAD00411)

Item no.	OAAD00411
Manufacturer	AVIVA Systems Biology
Amount	0.1mg
Category	Neuroscience Neuroinflammation Antibodies Western Blot ELISA Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, ELISA
Clone	1A7B8
Specific against	Human
Host	Mouse
Isotype	IgG1 kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Gene symbol	CCL2
Protein name	C-C motif chemokine 2
Gene id	6347
Description of target	Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH.
Clonality	Monoclonal
Formulation	Antibodies are purified by protein A affinity chromatography.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

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Delivery expected until 8/30/2024