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Anti-p70S6K Polyclonal Antibody (OAAI00474)

Anti-p70S6K Polyclonal Antibody (OAAI00474)

Item no.	OAAI00474
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Western Blot ELISA Primary Antibodies Astrocytoma
Type	Antibody Polyclonal
Applications	WB, ELISA
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	S6K, PS6K, S6K1, STK14A, p70-S6K, p70 S6KA, p70-alpha, S6K-beta-1, p70(S6K)-alpha
Similar products	p70-S6K, STK14A, PS6K, S6K, S6K1, p70(S6K)-alpha, p70-alpha, S6K-beta-1, p70 S6KA
Available
Gene symbol	RPS6KB1
Molecular weight	70 kDa
Gene id	6198
Reconstitution and storage	The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity. Avoid repeated freezing thawing cycles.
Description of target	S6 kinase, or p70 S6 Kinase, a mitogen activated Ser/Thr protein kinase, is required for cell growth and G1 cell cycle progression. P70 S6 Kinase and single 4E-BP are phosphorylated via the insulin and target of rapamycin (TOR) signaling pathway which is independent of PI3K and AKT activity. On the other hand, the oncogenic transformation by P3k and Akt is dependent on targets that control translation: transforming activity , which is correlated with phosphorylation and activation of S6K and eliminated by the mTOR inhibitor rapamycin. S6K phosphorylates the S6 protein of the 40S ribosomal subunit.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification.
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to the C-terminus of Human p70S6K protein. This sequence is identical within Human, Rat, Mouse, bovine, chicken and dog.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 8/30/2024

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