Manufacturer |
AVIVA Systems Biology
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat, Porcine, Rabbit, Fish, Guinea Pig, Canine, Equine |
Format |
Lyophilized powder |
Applications |
WB |
Amount |
100ul |
Host |
Rabbit |
Item no. |
ARP65744_P050 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
CCFDN, FCP1 |
Gene symbol |
CTDP1 |
Protein name |
RNA polymerase II subunit A C-terminal domain phosphatase |
Protein size |
867 |
Molecular weight |
93kDa |
Subunit |
A C-terminal domain phosphatase |
Product format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Gene id |
9150 |
Reconstitution and storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Partner proteins |
UBC. CDK9. UPP1. PPP2CA. PPP1CA. POLR2A. POLR2C. GRK5. ELP2. ELP3. SUMO2. PRKDC. CDK8. CDK7. INTS8. MED15. MED4. INTS6. INTS1. INTS7. MED16. MED6. MED24. MED7. MED26. MED17. MED23. MED14. MED1. MED8. MED25. INTS3. POLR2J. ERH. POLR2B. STK38. PRMT5. HIST1H |
Description of target |
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Homology |
Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85% |
Purification |
Affinity Purified |
Clonality |
Polyclonal |
Immunogen |
The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTDP1 |
Drywet |
Wet Ice |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.