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TNIP1 antibody - N-terminal region (ARP61715_P050)

TNIP1 antibody - N-terminal region (ARP61715_P050)

Manufacturer	AVIVA Systems Biology
Category	Neuroscience Neuroinflammation Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Signaling Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse
Format	Lyophilized powder
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	ARP61715_P050
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	ABIN-1, KIAA0113, NAF1, VAN, nip40-1
Gene symbol	TNIP1
Protein name	TNFAIP3-interacting protein 1
Protein size	636
Molecular weight	70kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	10318
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	HDDC3. MAGEB18. CFAP53. TXLNA. CCDC112. MOB3C. SYT6. TCEANC2. MOB1B. MAP1LC3A. NIFK. FAM161A. MAP1LC3B. TNIP3. SNIP1. CDIP1. NME7. MAGEH1. GABARAPL2. PNKP. MORF4L1. RALBP1. ZNHIT1. NDC80. TNIP1. OPTN. MORF4L2. AP1M1. TAX1BP1. ZBTB25. UBC. TNFAIP3. TCEA2.
Description of target	TNIP1 interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. TNIP1 increases cell surface CD4(T4) antigen expression. TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. TNIP1 may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.
Homology	Human: 100%; Mouse: 82%
Purification	Affinity Purified
Clonality	Polyclonal
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Delivery expected until 7/26/2024

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