Item no. |
ARP59681_P050 |
Manufacturer |
AVIVA Systems Biology
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Lyophilized powder |
Applications |
WB |
Specific against |
Human, Mouse, Rat, Porcine, Rabbit, Fish, Guinea Pig, Bovine, Canine, Equine, Sheep |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
123F2, NORE2A, RASSF1A, RDA32, REH3P21 |
Similar products |
RASSF1 |
Available |
|
Gene symbol |
RASSF1 |
Protein name |
Ras association domain-containing protein 1 |
Protein size |
270 |
Molecular weight |
30kDa |
Product format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Gene id |
11186 |
Reconstitution and storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Partner proteins |
FBXW11. MDM2. DAXX. SUV39H2. KDM1A. SUV39H1. STK4. STK3. CDC20. SAV1. MAST2. HUWE1. LATS1. BTRC. UBC. ID1. GSK3B. C7orf25. C8orf33. KCNE3. CUL4A. DDB1. Rassf1. SKP2. AURKB. AURKA. SKP1. CUL1. NUDT10. MOAP1. CNKSR1. MAP1S. EXOSC8. RASSF5. TNFRSF10A. E4F1. |
Description of target |
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Homology |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 85% |
Purification |
Affinity Purified |
Clonality |
Polyclonal |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human RASSF1 |
Drywet |
Wet Ice |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.