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KEAP1 antibody - C-terminal region (ARP38981_P050)

KEAP1 antibody - C-terminal region (ARP38981_P050)

Manufacturer	AVIVA Systems Biology
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Adenocarcinoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat, Rabbit, Guinea Pig, Bovine, Canine, Equine
Format	Lyophilized powder
Applications	WB, IHC
Amount	100ul
Host	Rabbit
Item no.	ARP38981_P050
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	INrf2, KLHL19
Gene symbol	KEAP1
Protein name	Kelch-like ECH-associated protein 1
Protein size	624
Molecular weight	70kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	9817
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	OXR1. ZSCAN32. LSM3. KLHL3. FBXW11. MAPKBP1. NUDT4. DPP3. RBX1. ATG5. SQSTM1. PTMA. PRKAG1. NFE2L2. MAD2L1. GYPA. ETF1. BCL2. CUL3. RECK. UBC. PGAM5. FAM117B. WDR83. CCNB1IP1. HSP90AA1. XPO1. MCMBP. KEAP1. SLK. MCM3. IKBKB. AMER1. GPRASP2. PRKCE. NFE2L1.
Description of target	This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Homology	Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%
Purification	Affinity Purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the C terminal region of human KEAP1
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 7/26/2024

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