Item no. |
ARP48632_P050 |
Manufacturer |
AVIVA Systems Biology
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Lyophilized powder |
Applications |
WB |
Specific against |
Human, Mouse, Rat, Porcine, Rabbit, Fish, Guinea Pig, Bovine, Canine, Equine |
Host |
Rabbit |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
BL44, GCK, RAB8IP |
Similar products |
MAP4K2 |
Available |
|
Gene symbol |
MAP4K2 |
Protein name |
Mitogen-activated protein kinase kinase kinase kinase 2 |
Protein size |
820 |
Molecular weight |
91kDa |
Product format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Gene id |
5871 |
Reconstitution and storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Partner proteins |
HSP90AA1. UBC. MAP3K11. MAP3K1. POT1. MCM3AP-AS1. NACAD. SNRNP35. PRDX4. SERPINA4. HNRNPA2B1. XRCC6. DEFB1. TRAF2. RAB8A. MAP2K4. |
Description of target |
MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. |
Homology |
Cow: 100%; Dog: 93%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 85%; Rat: 100%; Zebrafish: 92% |
Purification |
Affinity Purified |
Clonality |
Polyclonal |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K2 |
Drywet |
Wet Ice |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.