Item no. |
OAPC00213 |
Manufacturer |
AVIVA Systems Biology
|
Amount |
100 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots. |
Applications |
WB |
Specific against |
Human, Mouse, Rat, Fish, Bovine, Canine, Gallus |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Available |
|
Gene symbol |
MAP2K5 |
Protein name |
Dual specificity mitogen-activated protein kinase kinase 5 |
Molecular weight |
ca.49kDa |
Product format |
Liquid. 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots. |
Gene id |
29568 |
Reconstitution and storage |
Store at -20C; stable for at least one year. |
Description of target |
MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 (Zhou et al., 1995) whereas MEK5 itself is regulated by MEKK3 (Chao et al., 1999). An important link between MEK5 and metastatic prostrate cancer has been demonstrated (Mehta et.al., 2003). Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation (Cameron et al., 2004). |
Purification |
Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns. |
Clonality |
Polyclonal |
Immunogen |
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser311, Thr315 of MEK5. |
Drywet |
Wet Ice |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.