Item no. |
ARP51333_P050 |
Manufacturer |
AVIVA Systems Biology
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Lyophilized powder |
Applications |
WB |
Specific against |
Human, Mouse, Rat, Rabbit, Guinea Pig, Bovine, Canine, Equine |
Host |
Rabbit |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
CDC45, CDC45L2, PORC-PI-1, CDC45L |
Similar products |
CDC45L |
Available |
|
Gene symbol |
CDC45 |
Protein name |
Cell division control protein 45 homolog |
Protein size |
566 |
Molecular weight |
65kDa |
Product format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Gene id |
8318 |
Reconstitution and storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Partner proteins |
CEP55. UBC. FBXO6. DTD1. TOPBP1. CAMK1G. MCM10. TRAPPC3. ORC3. ORC5. CDKN2A. CDKN1A. ALB. MRE11A. CUL3. NEDD8. CDK2. L3MBTL1. HIST1H3A. CCL2. MCM7. MCM4. MCM3. ORC2. POLA1. CDK4. ORC6. ORC1. MCM6. |
Description of target |
CDC45L was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Homology |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100% |
Purification |
Affinity Purified |
Clonality |
Polyclonal |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human CDC45L |
Drywet |
Wet Ice |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.