Manufacturer |
St John's Laboratory
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Isotype |
IgG |
Applications |
WB, IF, IHC-P |
Amount |
200ul |
Host |
Rabbit |
Item no. |
STJ97398-200 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
Anti-Microtubule-Associated Proteins 1a/1b Light Chain 3b antibody</br>Anti-Autophagy-Related Protein Lc3 B antibody</br>Anti-Autophagy-Related Ubiquitin-Like Modifier Lc3 B antibody</br>Anti-Map1 Light Chain 3-Like Protein 2 antibody</br>Anti-Map1a/Map1b |
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
Q9GZQ8 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Description |
MAP LC3 beta is a protein encoded by the MAP1LC3B gene which is approximately 14, 7 kDa. MAP LC3 beta is localised to the cytoplasm, cytoskeleton and autophagosome membrane. It is involved in pathways such as vesicle-mediated transport, pink/parkin mediated mitophagy, ferroptosis, cellular senescence and the autophagy pathway. MAP LC3 beta is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and plays an important role in neurogenesis. MAP LC3 beta is expressed most abundantly in the heart, brain, skeletal muscle and testis and less expressed in liver. Mutations in the MAP1LC3B gene result in sporadic pheochromocytoma, lacrimal gland adenocarcinoma and spastic paraplegia STJ97398 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous MAP LC3 beta protein. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant Protein |
Short Description |
Rabbit polyclonal against MAP LC beta |
Tissue specificity |
Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver. |
Cellular localization |
CytoplasmCytoskeletonEndomembrane SystemLipid-AnchorCytoplasmic VesicleAutophagosome MembraneAutophagosomeLc3-Ii Binds To The Autophagic MembranesLocalizes Also To Discrete Punctae Along The Ciliary Axoneme (By Similarity) |
Dilution range |
WB 1:1000-2000IHC 1:200-500IF 1:200 |
Alternative names |
Anti-Microtubule-Associated Proteins 1a/1b Light Chain 3b antibodyAnti-Autophagy-Related Protein Lc3 B antibodyAnti-Autophagy-Related Ubiquitin-Like Modifier Lc3 B antibodyAnti-Map1 Light Chain 3-Like Protein 2 antibodyAnti-Map1a/Map1b Light Chain 3 B antibodyAnti-Map1a/Map1b Lc3 B antibodyAnti-Microtubule-Associated Protein 1 Light Chain 3 Beta antibodyAnti-MAP1LC3B MAP1ALC3 antibody |
Protein name |
Microtubule-Associated Proteins 1a/1b Light Chain 3bAutophagy-Related Protein Lc3 BAutophagy-Related Ubiquitin-Like Modifier Lc3 BMap1 Light Chain 3-Like Protein 2Map1a/Map1b Light Chain 3 BMap1a/Map1b Lc3 BMicrotubule-Associated Protein 1 Light Chain 3 Beta |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.