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Rabbit anti-Phospho-MTOR (Thr2446) Polyclonal Antibody

Rabbit anti-Phospho-MTOR (Thr2446) Polyclonal Antibody

Item no.	RD85955A-120uL
Manufacturer	Reddot Biotech
Amount	120 uL
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, ELISA
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1),FK506 binding protein 12 rapamycin associated protein 1,FK506 binding protein 12 rapamycin associated protein 2,FK506 binding protein 12 rapamycin complex associated protein 1,FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP rapamycin associated protein,FKBP12 rapamycin complex associated protein,FKBP12-rapamycin complex-associated protein 1,FKBP12-rapamycin complex-associated protein,FLJ44809,FRAP,FRAP1,FRAP2,Mammalian target of rapamycin,Mechanistic target of rapamycin,mTOR,MTOR,OTTHUMP00000001983,RAFT1,Rapamycin and FKBP12 target 1,Rapamycin associated protein FRAP2,Rapamycin target protein 1,Rapamycin target protein,RAPT1,Serine/threonine-protein kinase mTOR
Available
Background	MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is Kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. The antibody is specific to MTOR.
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Clonality	Polyclonal
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, ELISA 1:10000
Immunogen	Synthesized peptide derived from human mTOR around the phosphorylation site of Thr2446
Purification_Method	Affinity purification
Storage	Store at -20℃. Avoid repeated freeze / thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 120 uL

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Delivery expected until 9/20/2024

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