Alias |
GLC10,GLC1O,Neurotrophic factor 4,Neurotrophic factor 5,Neurotrophin 4,Neurotrophin 4/5,Neurotrophin 5 (neurotrophin 4/5),Neurotrophin 5,Neurotrophin-4,Neurotrophin-5,Neutrophic factor 4,Neutrophic factor 5,NT 4,NT 4/5,NT 5,NT-4,NT-5,NT4,NT4/5,NT4P,NT5,NTF4,NTF4,NTF5 |
Background |
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. |