Alias |
0910001N05Rik,1810032P22Rik,AU019504,D2Ertd52e,FLJ10931,OTTHUMP00000030340,OTTHUMP00000062927,OTTMUSP00000003367,OTTMUSP00000003368,RP11-504H3.2,RP23-35E16.2,snoRNA MBI-43,SNX 5,SNX5,SNX5,Sorting nexin 5,Sorting nexin-5 |
Background |
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. |