Alias |
IBP1,IGF I,IGF IA,IGF IB,IGF-I,Igf1,IGF1,IGF1A,IGFI,IGFIA,Insulin like growth factor 1 (somatomedin C),Insulin like growth factor 1,Insulin like growth factor IA,Insulin like growth factor IB,Insulin-like growth factor I,Mechano growth factor,MGF,OTTHUMP00000195080,OTTHUMP00000195081,OTTHUMP00000195082,OTTHUMP00000195083,OTTHUMP00000195084,Somatomedia C,Somatomedin C,Somatomedin-C |
Background |
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. |