Manufacturer |
Reddot Biotech
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse |
Isotype |
IgG |
Applications |
WB, IHC, ELISA |
Amount |
120 uL |
Host |
Rabbit |
Item no. |
RD79910A-120uL |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
AA690181,CD215,I15RA,IL 15R alpha,IL-15 receptor subunit alpha,IL-15R-alpha,IL-15RA,Il15ra,Interleukin 15 receptor alpha,Interleukin 15 receptor subunit alpha,MGC104179,sIL-15 receptor subunit alpha,sIL-15R-alpha,sIL-15RA,Soluble interleukin 15 receptor subunit alpha,Soluble interleukin-15 receptor subunit alpha |
Background |
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. |
Buffer |
PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Clonality |
Polyclonal |
Concentration |
0.5mg/mL |
Dilution |
WB 1:200-1:1000, IHC 1:50-1:200 |
Immunogen |
Synthetic peptide of human IL15RA |
Purification_Method |
Affinity purification |
Storage |
Store at -20℃. Avoid repeated freeze / thaw cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.