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HIF1AN Polyclonal Antibody

HIF1AN Polyclonal Antibody

Item no.	RD77085A-200uL
Manufacturer	Reddot Biotech
Amount	200 uL
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC, ELISA
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DKFZp762F1811,Factor inhibiting HIF-1,Factor inhibiting HIF1,FIH 1,FIH-1,FIH1,FLJ20615,FLJ22027,HIF1AN,HIF1N,Hypoxia inducible factor 1 alpha inhibitor,Hypoxia inducible factor 1 alpha subunit inhibitor,Hypoxia inducible factor asparagine hydroxylase,Hypoxia-inducible factor 1-alpha inhibitor,Hypoxia-inducible factor asparagine hydroxylase,Peptide aspartate beta dioxygenase
Available
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Format (Type)	Polyclonal Antibody
Manufactures Category	Antibodies
Background	Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm.
Concentration	0.6 mg/mL
Immunogen	Synthetic peptide of human HIF1AN
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Dilution	WB 1:500-1:2000, IHC 1:50-1:300
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 uL

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Delivery expected until 10/25/2024

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