Alias |
CD_antigen=CD116,CD116,CD116 antigen,CDw116,Colony stimulating factor 2 receptor alpha chain,Colony stimulating factor 2 receptor alpha low affinity,Colony stimulating factor 2 receptor alpha subunit,CSF 2R,CSF2R,CSF2RA,CSF2RAX,CSF2RAY,CSF2RX,CSF2RY,GM CSF R alpha,GM CSF receptor alpha subunit,GM-CSF-R-alpha,GMCSFR,GMCSFR-alpha,GMR-alpha,Granulocyte macrophage colony stimulating factor receptor alpha chain,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,SMDP4 |
Background |
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. |