« Back
Home /
Rabbit anti-NFκB-p65 Polyclonal Antibody

Rabbit anti-NFκB-p65 Polyclonal Antibody

Item no.	RD71541A-60uL
Manufacturer	Reddot Biotech
Amount	60 uL
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, ELISA
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Avian reticuloendotheliosis viral (v rel) oncogene homolog A,MGC131774,NF kappa B p65delta3,NFKB3,Nuclear Factor NF Kappa B p65 Subunit,Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B cells 3,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3,OTTHUMP00000233473,OTTHUMP00000233474,OTTHUMP00000233475,OTTHUMP00000233476,OTTHUMP00000233900,p65,p65 NF kappaB,p65 NFkB,relA,TF65,Transcription factor p65,v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)),V rel avian reticuloendotheliosis viral oncogene homolog A,v rel reticuloendotheliosis viral oncogene homolog A (avian),V rel reticuloendotheliosis viral oncogene homolog A,nuclear factor of kappa light polypeptide gene enhancer in B cells 3,p65
Available
Background	Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor NFκB (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp κB sequence in the immunoglobulin κ light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NFκB is activated and NFκB is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Clonality	Polyclonal
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, ELISA 1:40000
Immunogen	Synthesized peptide derived from human NFκB-p65 around the non-phosphorylation site of Thr505.
Purification_Method	Affinity purification
Storage	Store at -20℃. Avoid repeated freeze / thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 60 uL

available

Delivery expected until 8/23/2024