Alias |
Annexin A2,Annexin II,Annexin II, heavy chain,Annexin-2,ANX 2,ANX2,ANX2L4,ANXA2,ANXA2,arylsulfatase B,CAL1H,Calpactin I heavy chain,calpactin I heavy polypeptide (p36),Calpactin I heavy polypeptide,Calpactin-1 heavy chain,chromobindin 8,Chromobindin-8,Epididymis secretory protein Li 270,HEL S 270,LIP2,Lipocortin II,LPC2,LPC2D,p36,P36 protein,PAP-IV,Placental anticoagulant protein IV,Protein I |
Background |
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |