Alias |
C3DR,CD 21,CD21,Complement C3d receptor 2,Complement C3d receptor,Complement component (3d/Epstein Barr virus) receptor 2,Complement receptor type 2,CR,Cr2,CR2,CVID7,EBV receptor,EBV-R,Epstein Barr virus receptor,Epstein-Barr virus receptor,EVBR,SLEB9 |
Background |
CD21 is also called the complement receptor 2 type (CR2) and EB virus receptor, is a member of the complement activation regulators family.CD21 is mainly distributed in mature B cells, dendritic cells in lymphoid follicles, and part of the T cells. The functions of CD21 include promoting proliferation of B cell, mediating transformation of EBV to B cells and participating in immune memory. It is mainly used for diagnosis of follicular cell tumors and study of regulation of immune complement activation. |