« Back
Home /
STAT1 Polyclonal Antibody

STAT1 Polyclonal Antibody

Item no.	RD70027A-60uL
Manufacturer	Reddot Biotech
Amount	60 uL
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human, Rat
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Signal transducer and activator of transcription 1 91kD,CANDF7,DKFZp686B04100,IMD31A,IMD31B,IMD31C,ISGF 3,ISGF-3,OTTHUMP00000163552,OTTHUMP00000165046,OTTHUMP00000165047,OTTHUMP00000205845,Signal transducer and activator of transcription 1 91kDa,Signal transducer and activator of transcription 1,91kD,Signal transducer and activator of transcription 1-alpha/beta,STAT 1,Stat1,STAT1,STAT91,Transcription factor ISGF 3 components p91 p84,Transcription factor ISGF-3 components p91/p84
Available
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Format (Type)	Polyclonal Antibody
Manufactures Category	Antibodies
Background	Signal transducer and activator of transcription that mediates signaling by interferons (IFNs). Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state.
Concentration	2 mg/mL
Immunogen	Recombinant human Zinc finger protein SNAI1 protein
Buffer	PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method	Affinity purification
Dilution	WB 1:500-1:1000, IHC 1:50-1:100
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 60 uL

available

Delivery expected until 10/25/2024

Express Delivery: Save 25 days

Compare

Add to wishlist

Recommend by mail