Item no. |
PRS-XW-7097-0.05mg |
Manufacturer |
ProSci
|
Amount |
0.05 mg |
Category |
|
Type |
Antibody Primary |
Format |
Liquid |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Chicken |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Cell division control protein 42 homolog, G25K GTP-binding protein, G25K, CDC42Hs, CDC42 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Signal Transduction |
Immunogen |
1-191 |
Applications |
CDC42 antibody can be used for the detection of CDC42 by Western blot, may also work for IHC and ICC. |
Predicted Molecular Weight |
6.6 kDa (calculated) |
Purification |
Antigen affinity-purified |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Phosphate-Buffered Saline. No preservatives added. |
Concentration |
1 mg/mL |
Storage Conditions |
CDC42 antibody can be stored at 4˚ C for short term (weeks). Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
CDC42 |
Accession # |
NP_001782.1 |
Protein Gi # |
4757952 |
Ncbi Gene Id # |
998 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
CDC42 |
Ncbi Official Full Name |
cell division cycle 42 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P60953 |
Background |
Cell division cycle 42 isoform 1; cell division cycle 42 (GTP-binding protein, 25kD). This protein is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcript variants. |
Background References 1 |
Etienne-Manneville, S., Hall, A. Cdc42 regulates GSK-3-beta and adenomatous polyposis coli to control cell polarity. Nature 421: 753-756, 2003. |
1st Image Caption |
Western blot: E coli-derived fusion protein as test antigen. XW-7097 dilution 1:2000. Colorimetric method for signal development. Predicted band size : 24 kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.