CDC42 Antibody

blue ice or RT

1-191

6.6 kDa (calculated)

Polyclonal

Phosphate-Buffered Saline. No preservatives added.

CDC42 antibody can be stored at 4˚ C for short term (weeks). Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

None

NP_001782.1

998

CDC42

Homo sapiens

Cell division cycle 42 isoform 1; cell division cycle 42 (GTP-binding protein, 25kD). This protein is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcript variants.

Western blot: E coli-derived fusion protein as test antigen. XW-7097 dilution 1:2000. Colorimetric method for signal development. Predicted band size : 24 kDa