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Dopamine b-Hydroxylase Antibody

Dopamine b-Hydroxylase Antibody

Item no.	PRS-XPS-2002-0.1mL
Manufacturer	ProSci
Amount	0.1 mL
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human, Rat, Bovine, Ovine
Host	Sheep
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Shipping	blue ice or RT
By Research Area	Neuroscience
Immunogen	DBH polyclonal antibody was raised against a synthetic peptide from the N-terminal region of human DBH, conjugated to keyhole limpet hemocyanin.
Applications	Applications include Dot Blots (DB) and Western Blots (WB). Sheep anti-DBH recognizes DBH in bovine, human, monkey and rat tissues. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.
Specificity	Dopamine b-Hydroxylase, NT antibody is specific immunolabeling of the ~75k DBH protein in Western blots of human adrenal medulla.
Predicted Molecular Weight	75
Purification	Affinity Purified
Clonality	Polyclonal
Conjugate	Unconjugated
Storage Conditions	For long term storage –80˚ C is recommended, but shorter term storage at –20˚ C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.
Disclaimer	This product is for research use only.
Modifications	None
Ncbi Official Symbol	DBH
Accession #	P09172
Protein Gi #	158517849
Ncbi Gene Id #	1621
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	DBH
Ncbi Official Full Name	dopamine beta-hydroxylase (dopamine beta-monooxygenase)
Ncbi Organism	Homo sapiens
Swissprot #	P09172
Background	Dopamine beta-hydroxylase (DBH) catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. The expression of DBH is elevated during stress.
Background References 1	Sabban, E.L., Kvetnansky, R. "Stress-triggered activation of gene expression in catecholaminergic systems: dynamics of transcriptional events, " Trends Neurosci. 24 (2001) 91 - 98.
Background References 2	Nagatsu, I, Kobayashi, K, Fujii, T, Komori, K, Sekiguchi, K, Titani, K, Fujita, K, and Nagatsu, T. "Antibodies raised against different oligopeptide segments of human dopamine-β -hydroxylase, " Neuroscience Letters, 120 (1990) 141 - 145.
1st Image Caption	Dopamine beta-Hydroxylase, NT Antibody

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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