Item no. |
PRS-98-542-0.1mg |
Manufacturer |
ProSci
|
Amount |
0.1 mg |
Category |
|
Type |
Antibody Monoclonal |
Format |
Liquid |
Applications |
WB, IP, IHC, ICC, ELISA, IHC-P |
Specific against |
Mouse |
Host |
Rat |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Pgp-1, H-CAM, HUTCH-1, ECMR-III |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer, Immunology |
Immunogen |
(C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal clone BMS2 |
Applications |
CD44 Antibody [KM201] for use in flow cytometry assays. |
Specificity |
CD44 |
Clonality |
Monoclonal |
Clone |
[KM201] |
Isotype |
IgG1 |
Conjugate |
PE-Cy5 |
Buffer |
Supplied in PBS/NaN3 and a stabilizing agent |
Concentration |
0.1 mg/mL |
Storage Conditions |
Store vial at 2-8˚ C |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
Cd44 |
Accession # |
P15379 |
Ncbi Gene Id # |
12505 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
Cd44 |
Ncbi Official Full Name |
CD44 antigen |
Ncbi Organism |
Mus musculus |
Swissprot # |
P15379 |
Background |
CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells. |
1st Image Caption |
BALB/c mouse bone marrow cells were stained with Rat Anti-Mouse CD44-SPRD (Cat. No. 98-542). |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.