Item no. |
PRS-79-682-0.1mg |
Manufacturer |
ProSci
|
Amount |
0.1 mg |
Category |
|
Type |
Antibody Primary |
Format |
Liquid |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
NEP, SFE, CD10, CALLA, NEP, MME, MGC126681 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Stem Cell |
Immunogen |
CD10 antibody was raised against a peptide sequence around aa.6~10 (S-Q-M-D-I) derived from Human CD10. |
Applications |
Western Blot: 1:500 |
Specificity |
This antibody detects endogenous level of total CD10 protein. |
Predicted Molecular Weight |
100 kDa |
Purification |
Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration |
1 mg/mL |
Storage Conditions |
Store antibody at -20˚ C for up to one year. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
MME |
Accession # |
NP_000893.2 |
Protein Gi # |
116256329 |
Ncbi Gene Id # |
4311 |
Ncbi Official Symbol |
MME |
Ncbi Official Full Name |
membrane metallo-endopeptidase |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P08473 |
Background |
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
Background References 1 |
Yandle T. G., Brennan S. O., Espiner E. A., Nicholls M. G., Richards A. M. Peptides 10:891-894 (1989) Rice G. I., Thomas D. A., Grant P. J., Turner A. J., Hooper N. M. Biochem. J. 383:45-51 (2004) Morisaki N., Moriwaki S., Sugiyama-Nakagiri Y., Haketa K., Takema Y., Imokawa G. J. Biol. Chem. 285:39819-39827 (2010) |
1st Image Caption |
Western blot analysis of extract from Rat kidney tissue using CD10 Antibody. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.