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CD115 Antibody [AFS98] (FITC)

CD115 Antibody [AFS98] (FITC)

Item no.	PRS-76-878-0.025mg
Manufacturer	ProSci
Amount	0.025 mg
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Format	liquid
Applications	FC
Specific against	Mouse
Host	Rat
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Fms, CD115, Csfmr, Fim-2, CSF-1R, M-CSFR, M-CSF-R, AI323359, Csf1r
Available
Shipping	blue ice or RT
By Research Area	Innate Immunity
Specificity	The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages.
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality	Monoclonal
Clone	AFS98
Isotype	Rat IgG2a, kappa
Conjugate	FITC
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration	batch dependent
Storage Conditions	The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	Csf1r
Ncbi Gene Id #	12978
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	Csf1r
Ncbi Official Full Name	colony stimulating factor 1 receptor
Ncbi Organism	Mus musculus
Swissprot #	P09581
Background	The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
Background References 1	Murayama, T., Yokode, M., Kataoka, H., Imabayashi, T., Yoshida, H., Sano, H., ... Kita, T. (1999). Intraperitoneal administration of antic-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein Edeficient mice.Circulation, 99(13), 1740-1746.
Background References 2	Sudo, T., Nishikawa, S., Ogawa, M., Kataoka, H., Ohno, N., Izawa, A., Hayashi, S. (1995). Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M.Oncogene, 11(12), 2469-2476.
Background References 3	Yoshino, M., Yamazaki, H., Yoshida, H., Niida, S., Nishikawa, S. I., Ryoke, K., ... Hayashi, S. I. (2003). Reduction of osteoclasts in a critical embryonic period is essential for inhibition of mouse tooth eruption.Journal of Bone and Mineral Research, 18(1), 108-116.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.025 mg

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Delivery expected until 10/4/2024

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