Comparison

CD29 Antibody [TS2/16] (PE)

Item no. PRS-76-792-100tests
Manufacturer ProSci
Amount 100 tests
Category
Type Antibody Monoclonal
Format liquid
Applications FC
Specific against Human
Host Mouse
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, ITGB1
Available
Shipping
blue ice or RT
By Research Area
Cancer
Specificity
The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality
Monoclonal
Clone
TS2/16
Isotype
Mouse IgG1, kappa
Conjugate
PE
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration
batch dependent
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
ITGB1
Ncbi Gene Id #
3688
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
ITGB1
Ncbi Official Full Name
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
Ncbi Organism
Homo sapiens
Swissprot #
P05556
Background
The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells. It forms the VLA-(1-6) molecules with integrin alpha-(1-6) and is involved in the adhesion between cell-cell and cell-matrix. The TS2/16 antibody has been found to activate beta 1 integrins.
Background References 1
Ridger, V. C., Wagner, B. E., Wallace, W. A., Hellewell, P. G. (2001). Differential effects of CD18, CD29, and CD49 integrin subunit inhibition on neutrophil migration in pulmonary inflammation.The Journal of Immunology, 166(5), 3484-3490.
Background References 2
Noto, K., Kato, K., Okumura, K., Yagita, H. (1995). Identification and functional characterization of mouse CD29 with a mAb.International immunology, 7(5), 835-842.
Background References 3
Sangaletti, S., Di Carlo, E., Gariboldi, S., Miotti, S., Cappetti, B., Parenza, M., ... Colombo, M. P. (2008). Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis.Cancer research, 68(21), 9050-9059.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 tests
Available: In stock
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