Item no. |
PRS-63-891-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, IHC-P |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Centromere protein K, CENP-K, Interphase centromere complex protein 37, Protein AF-5alpha, p33, CENPK, ICEN37 |
Available |
|
Shipping |
blue ice or RT |
Immunogen |
This CENPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-266 amino acids from the C-terminal region of human CENPK. |
Applications |
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 |
Predicted Molecular Weight |
32 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
CENPK |
Accession # |
Q9BS16 |
Protein Gi # |
74732954 |
Ncbi Gene Id # |
64105 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
CENPK |
Ncbi Official Full Name |
Centromere protein K |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q9BS16 |
Background |
CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression. |
Background References 1 |
Cheeseman, I.M., et.al., Mol. Biol. Cell 19 (2), 587-594 (2008) |
Background References 2 |
Izuta, H., et.al., Genes Cells 11 (6), 673-684 (2006) |
Background References 3 |
Okada, M., et.al., Nat. Cell Biol.(5), 446-457 (2006) |
1st Image Caption |
Western blot analysis of CENPK Antibody in mouse liver tissue lysates (35ug/lane) |
2nd Image Caption |
Formalin-fixed and paraffin-embedded human brain tissue reacted with CENPK Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.