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LOX Antibody

LOX Antibody

Item no.	PRS-63-793-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Neuroscience Neuroinflammation Antibodies Cell Biology Cell Culture Cytokines Flow Cytometry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein-lysine 6-oxidase, Lysyl oxidase, LOX
Available
Shipping	blue ice or RT
By Research Area	Cancer, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Immunogen	This LOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
Applications	For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Predicted Molecular Weight	47 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	LOX
Accession #	P28300
Ncbi Gene Id #	4015
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	LOX
Ncbi Official Full Name	Protein-lysine 6-oxidase
Ncbi Organism	Homo sapiens
Swissprot #	P28300
Background	LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression.
Background References 1	Mariani, T.J., et.al., Matrix 12 (3), 242-248 (1992)
1st Image Caption	Western blot analysis of LOX Antibody in MDA-MB468 cell line lysates (35ug/lane)
2nd Image Caption	Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024

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