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AK3 Antibody

AK3 Antibody

Item no.	PRS-63-413-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Enzymes Prostaglandin Synthases Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Adenylate kinase 4, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03170}, AK 4 {ECO:0000255\|HAMAP-Rule:MF_03170}, 27410 {ECO:0000255\|HAMAP-Rule:MF_03170}, 2746 {ECO:0000255\|HAMAP-Rule:MF_03170}, Adenylate kinase 3-like {ECO:0000255\|HAMAP-Rule:MF_03170}, GTP:AM
Available
Shipping	blue ice or RT
By Research Area	Obesity, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Rat
Immunogen	This AK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the C-terminal region of human AK3.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight	25 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	AK4
Accession #	P27144
Protein Gi #	125157
Ncbi Gene Id #	100507855, 205
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	AK4
Ncbi Official Full Name	Adenylate kinase 4, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03170}
Ncbi Organism	Homo sapiens
Swissprot #	P27144
Background	AK3 is a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated.
Background References 1	Van Rompay, A.R., et al., Eur. J. Biochem. 261(2):509-517 (1999).
Background References 2	Yoneda, T., et al., Brain Res. Mol. Brain Res. 62(2):187-195 (1998).
Background References 3	Xu, G., et al., Genomics 13(3):537-542 (1992).
Background References 4	Robson, E.B., et al., Cytogenet. Cell Genet. 32 (1-4), 144-152 (1982).
1st Image Caption	Antibody is used in Western blot to detect AK3 in mouse kidney tissue lysate.
2nd Image Caption	Western blot analysis of AK3 using rabbit polyclonal AK3 Antibody (C-term H38) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AK3 gene (Lane 2).
3rd Image Caption	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024

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