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FRIH Antibody

FRIH Antibody

Item no.	PRS-62-861-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Cell Biology Western Blot Cell Stainings ECM Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein, Ferritin heavy chain, N-terminally processed, FTH1, FTH, FTHL6
Available
Shipping	blue ice or RT
By Research Area	Obesity, Neuroscience, Signal Transduction
Immunogen	This FRIH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-180 amino acids from the C-terminal region of human FRIH.
Applications	For WB starting dilution is: 1:1000
Predicted Molecular Weight	21 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	FTH1
Accession #	P02794
Protein Gi #	120516
Ncbi Gene Id #	2495
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	FTH1
Ncbi Official Full Name	Ferritin heavy chain
Ncbi Organism	Homo sapiens
Swissprot #	P02794
Background	FRIH is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases.
Background References 1	Coffman, L.G., Proc. Natl. Acad. Sci. U.S.A. 106 (2), 570-575 (2009)
Background References 2	Sammarco, M.C., J. Biol. Chem. 283 (8), 4578-4587 (2008)
1st Image Caption	Western Blot at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: HT-29 whole cell lysate Lysates/proteins at 20 ug per lane.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024

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