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BF Antibody

BF Antibody

Item no.	PRS-62-850-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry Western Blot Cardiovascular Research Hypertension Primary Antibodies By Organ Colorectal Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Complement factor B, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, Complement factor B Ba fragment, Complement factor B Bb fragment, CFB, BF, BFD
Available
Shipping	blue ice or RT
By Research Area	Immunology
Immunogen	This BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 amino acids from the Central region of human BF.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight	86 kDa
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CFB
Accession #	P00751
Protein Gi #	584908
Ncbi Gene Id #	629
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CFB
Ncbi Official Full Name	Complement factor B
Ncbi Organism	Homo sapiens
Swissprot #	P00751
Background	BF is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Background References 1	Baatz, H., Klin Monatsbl Augenheilkd 226 (8), 654-658 (2009)
Background References 2	Goring, K., Am. J. Physiol., Cell Physiol. 296 (5), C1140-C1150 (2009)
1st Image Caption	Western blot analysis of BF Antibody in HepG2 cell line and mouse liver tissue lysates (35ug/lane)
2nd Image Caption	BF Antibody IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024

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