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PDK4 Antibody

PDK4 Antibody

Item no.	PRS-62-613-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Metabolism Diabetes Neural Signaling Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Melanoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4, PDK4, PDHK4
Available
Shipping	blue ice or RT
By Research Area	Obesity, Signal Transduction
Immunogen	This PDK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-277 amino acids from human PDK4.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight	46 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	PDK4
Accession #	Q16654
Protein Gi #	3183120
Ncbi Gene Id #	5166
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	PDK4
Ncbi Official Full Name	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
Ncbi Organism	Homo sapiens
Swissprot #	Q16654
Background	PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Background References 1	Rosa, G., et al., Obes. Res. 11(2):176-182 (2003). Razeghi, P., et al., Cardiology 97(4):203-209 (2002). Rowles, J., et al., J. Biol. Chem. 271(37):22376-22382 (1996). Gudi, R., et al., J. Biol. Chem. 270(48):28989-28994 (1995).
1st Image Caption	Western blot analysis of PDK4 Antibody (E265) in CEM cell line lysates (35ug/lane)
2nd Image Caption	Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with PDK4-E265, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024

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