Item no. |
PRS-62-245-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer, Cell Cycle, Neuroscience, Signal Transduction |
Immunogen |
This Kallikrein 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from the C-terminal region of human Kallikrein 3. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
29 kDa |
Purification |
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
KLK3 |
Accession # |
P07288 |
Protein Gi # |
130989 |
Ncbi Gene Id # |
354 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
KLK3 |
Ncbi Official Full Name |
Prostate-specific antigen |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P07288 |
Background |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. |
Background References 1 |
Binnie, M.C., et al., Prostate 63(4):309-315 (2005). |
Background References 2 |
Habib, F.K., et al., Int. J. Cancer 114(2):190-194 (2005). |
Background References 3 |
Laidler, P., et al., Arch. Biochem. Biophys. 435(1):1-14 (2005). |
Background References 4 |
Dallas, S.L., et al., J. Cell. Physiol. 202(2):361-370 (2005). |
1st Image Caption |
Western blot analysis of anti-KLK3 Pab in mouse brain tissue lysate |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.