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SYN3 Antibody

SYN3 Antibody

Item no.	PRS-62-038-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Synapsin-3, Synapsin III, SYN3
Available
Shipping	blue ice or RT
By Research Area	Neuroscience
Immunogen	This SYN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-388 amino acids from the Central region of human SYN3.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight	63 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	SYN3
Accession #	O14994
Ncbi Gene Id #	8224
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	SYN3
Ncbi Official Full Name	Synapsin-3
Ncbi Organism	Homo sapiens
Swissprot #	O14994
Background	This gene is a member of the synapsin gene family.Synapsins encode neuronal phosphoproteins which associate with thecytoplasmic surface of synaptic vesicles. Family members arecharacterized by common protein domains, and they are implicated insynaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases.The protein encoded by this gene shares the synapsin family domainmodel, with domains A, C, and E exhibiting the highest degree ofconservation. The protein contains a unique domain J, locatedbetween domains C and E. Based on this gene's localization to22q12.3, a possible schizophrenia susceptibility locus, and theestablished neurobiological roles of the synapsins, this familymember may represent a candidate gene for schizophrenia. The TIMP3gene is located within an intron of this gene and is transcribed inthe opposite direction.
Background References 1	Tsai, M.T., et al. Am. J. Med. Genet. 114(1):79-83(2002)
Background References 2	Kao, H.T., et al. J. Exp. Zool. 285(4):360-377(1999)
Background References 3	Porton, B., et al. J. Neurochem. 73(6):2266-2271(1999)
Background References 4	Kao, H.T., et al. Proc. Natl. Acad. Sci. U.S.A. 95(8):4667-4672(1998)
1st Image Caption	Western blot analysis in NCI-H460 cell line lysates (15ug/lane).
2nd Image Caption	SYN3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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