Item no. |
PRS-61-919-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Platelet-activating factor receptor, PAF-R, PAFr, PTAFR, PAFR |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Immunology, Signal Transduction, Growth Factor |
Immunogen |
This PTAFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-312 amino acids from the C-terminal region of human PTAFR. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
39 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
PTAFR |
Accession # |
P25105 |
Protein Gi # |
129557 |
Ncbi Gene Id # |
5724 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
PTAFR |
Ncbi Official Full Name |
Platelet-activating factor receptor |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P25105 |
Background |
PTAFR shows structural characteristics of the rhodopsin(MIM 180380) gene family and binds platelet-activating factor(PAF). PAF is a phospholipid(1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has beenimplicated as a mediator in diverse pathologic processes, such asallergy, asthma, septic shock, arterial thrombosis, andinflammatory processes. |
Background References 1 |
Davila, S., et al. Genes Immun. (2010) In press : |
Background References 2 |
Hirota, N., et al. J. Biol. Chem. 285(8):5931-5940(2010) |
Background References 3 |
Kaneko, K., et al. J. Invest. Dermatol. 129(11):2567-2573(2009) |
Background References 4 |
Melnikova, V.O., et al. J. Biol. Chem. 284(42):28845-28855(2009) |
1st Image Caption |
Western Blot at 1:1000 dilution + A549 whole cell lysate Lysates/proteins at 20 ug per lane. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.