Item no. |
PRS-61-774-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Migration and invasion-inhibitory protein, IGFBP2-binding protein, Invasion-inhibitory protein 45, IIp45, MIIP, IIP45 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer, Neuroscience |
Immunogen |
This MIIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the C-terminal region of human MIIP. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
43 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
MIIP |
Accession # |
Q5JXC2 |
Protein Gi # |
296439302 |
Ncbi Gene Id # |
60672 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
MIIP |
Ncbi Official Full Name |
Migration and invasion-inhibitory protein |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q5JXC2 |
Background |
MIIP inhibits glioma cells invasion and down-regulates adhesion-and motility-associated genes such as NFKB2 and ICAM1. MIIP exhibits opposing effects to IGFBP2 on cell invasion. |
Background References 1 |
Wu, Y., et al. J. Biol. Chem. 285(6):3554-3560(2010) Song, F., et al. Cancer Res. 70(3):1024-1032(2010) Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009) |
1st Image Caption |
Western blot analysis of MIIP Antibody in ZR-75-1 cell line lysates (35ug/lane) |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.