Item no. |
PRS-61-477-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, FC |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Sigma non-opioid intracellular receptor 1, Aging-associated gene 8 protein, SR31747-binding protein, SR-BP, Sigma 1-type opioid receptor, SIG-1R, Sigma1-receptor, Sigma1R, hSigmaR1, SIGMAR1, OPRS1, SRBP |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer, Neuroscience, Signal Transduction |
Homology |
Predicted species reactivity based on immunogen sequence: Mouse, Rat |
Immunogen |
This OPRS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-81 amino acids from the N-terminal region of human OPRS1. |
Applications |
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 |
Predicted Molecular Weight |
25 kDa |
Purification |
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
SIGMAR1 |
Accession # |
Q99720 |
Protein Gi # |
74752153 |
Ncbi Gene Id # |
10280 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
SIGMAR1 |
Ncbi Official Full Name |
Sigma non-opioid intracellular receptor 1 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q99720 |
Background |
OPRS1 is a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. |
Background References 1 |
Cobos, E.J., J. Neurochem. 102 (3), 812-825 (2007) Maurice, T., Pharmacol. Biochem. Behav. 84 (4), 581-597 (2006) Lee, I.T., Eur. J. Pharmacol. 578 (2-3), 123-136 (2008) |
1st Image Caption |
Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane. |
2nd Image Caption |
Western blot analysis of OPRS1 using rabbit polyclonal OPRS1 Antibody.293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2). |
3rd Image Caption |
Flow cytometric analysis of NCI-H292 cells using OPRS1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.