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S adenosylhomocysteine hydrolase Antibody

S adenosylhomocysteine hydrolase Antibody

Item no.	PRS-61-463-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, AHCY, SAHH
Available
Shipping	blue ice or RT
By Research Area	Obesity, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Monkey
Immunogen	This S adenosylhomocysteine hydrolase (ACHY) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-432 amino acids from the C-terminal region of human S adenosylhomocysteine hydrolase (ACHY).
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight	48 kDa
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	AHCY
Accession #	P23526
Protein Gi #	20141702
Ncbi Gene Id #	191
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	AHCY
Ncbi Official Full Name	Adenosylhomocysteinase
Ncbi Organism	Homo sapiens
Swissprot #	P23526
Background	S-adenosylhomocysteine hydrolase (AHCY) catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.
Background References 1	Yideng, J., DNA Cell Biol. 26 (8), 603-611 (2007)
Background References 2	Arredondo-Vega, F.X., Ann. Hum. Genet. 53 (PT 2), 157-167 (1989)
Background References 3	Li, Q.S., Biochemistry 47 (17), 4983-4991 (2008)
1st Image Caption	Western blot analysis of anti-AHCY Antibody in HepG2 cell line lysates (35ug/lane)
2nd Image Caption	Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AHCY antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024